I work as a graduate research assistant in the DeFrate Musculoskeletal Bioengineering Laboratory under Dr. Lou DeFrate. My research focuses on quantifying cartilage deformations in the human knee, shoulder, and hip joints in vivo, using magnetic resonance imaging (MRI) and 3D solid modeling techniques. I also use novel quantitative MRI methods, such as T1rho and T2 mapping, to analyze the structure and composition of cartilage non-invasively to assess overall tissue health. Most recently, I have been working to develop image processing techniques to automatically isolate bones from MR images.
Figure 1. Exercise decreased cartilage thickness in the patella, as demonstrated in an ACL deficient knee. Red regions represent thicker cartilage, while blue regions represent thinner cartilage. (S = superior; I = inferior; M = medial; L = lateral).
*Figures above from Owusu-Akyaw et al. (2018).
Figure 2. Patellofemoral cartilage was sampled within 2.5 mm radius regions spanning the cartilage surfaces, enabling site-specific comparisons of cartilage thickness before and after exercise and between ACL deficient and intact knees. (A) Patellar cartilage. (B) Trochlear cartilage.